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3D tissue modelling system - RAFT

3D tissue modelling system - RAFT (Real Architecture for 3D Tissue).

RAFT (Real Architecture for 3D Tissue) is a new 3D tissue modelling system to enable scientists to create complex 3D tissue models from collagen, in a convenient, simple-to-use format.
  Developed by TAP in collaboration with leading tissue engineering academics, RAFT combines a novel patented process with a workstation and a range of consumables for making multi-cellular 3D tissue constructs rapidly, simply and reproducibly.
 

The RAFT process:

Using the RAFT 3D tissue modelling system, it takes less than one hour to create a strong 3D tissue construct with a high concentration of cells and collagen.
  To learn more, view the RAFT process animation which provides a simulation of the process - from experiment preparation, set up and incubation, through to the creation of the final construct.
  View the RAFT 3D tissue modelling system process animation

RAFT automates:
 
  • Rapidly produces 3D tissue constructs (less than 1 hour)
  • Uses collagen (the major component of extracellular matrix) - the ideal material for forming 3D tissues
  • Enables up to 24 tissue constructs to be produced simultaneously
  • Offers a choice of consumable formats – tissues can be made in standard wells or permeable membrane inserts for barrier assays or culture at an air/liquid interface
  • Supports complex cell co-culture, the tissue surface can be embossed with topology to mimic cells’ microenvironment, and then a different cell type cultured on the tissue surface
RAFT 3D tissue modelling system offers:
 
  • Creates a more realistic, ‘natural environment’ for scientists to study complex cell behaviour
  • Allows scientists to work with a wide range of complex 3D tissue models
  • Enables production of consistent, reproducible 3D tissue models using simple equipment
  • Makes efficient use of scarce primary cells and maintains differentiated phenotype
  • Improves lab productivity, with minimal time needed to produce multiple tissues for multiple experiments
  RAFT enables production of standardised, defined 3D culture conditions, in simple-to-use format.
Applications include:
 
  • Compound screening
  • Cell Biology
  • Safety pharmacology
  • Tissue engineering
  For more information on RAFT:
  Get more detail on 3D tissue modelling system - key applications
  Discuss your requirements with Ian Ransome, Sales Director
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