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There are striking differences
in morphology and biological response of
cells in a 3D environment compared to standard
2D culture, including differentiation, proliferation
and drug metabolism. However, adoption of
3D technologies into routine use has been
slow because they are technically demanding,
labour intensive and can give variable results. |
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RAFT
has been designed to overcome these issues,
and enables researchers to produce complex
3D cell cultures simply and conveniently. |
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The RAFT System is based
on a novel, patented process using collagen
to mimic closely an in vivo environment.
The RAFT plate, reagents and protocols together
allow multi-cellular 3D cell cultures to
be made rapidly and consistently in standard
plate formats. |
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For more information
visit: RAFT
- system overview |
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CompacT
SelecT has been chosen by a number
of organisations for large scale expansion
of cells, including mesenchymal and embryonic
stem cells, for research. |
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The CompacT format offers
walk-away automation in small footprint
system that could be fitted into most laboratories
in a space similar to a standard TC hood.
Most adherent mammalian cell lines can be
easily grow in the system, from standard
CHO stable cell lines to embryonic stem
cells, with minimal change from the standard
manual flask-based processing. |
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- ITI Life
Sciences chose CompacT SelecT
to develop a consistent bioprocess for
manufacturing high-quality undifferentiated
human embryonic stem (hES) cells
- Stem Cell
Sciences (SCS) chose CompacT
SelecT to culture several different
human and mouse stem cell lines for
supply to the world’s top pharmaceutical
companies.
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For more information
visit:
CompacT SelecT - system overview |
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Cell-IQ
can be used for a wide range of imaging
applications, quality control of growth
studies for stem cell colonies, monitoring
stem cell differentiation, tracking the
development of induced pluripotent stem
cells (iPS cells) and gene expression studies. |
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- The Karolinska
Institute’s Division of Obstetrics
and Gynaecology is using Cell-IQ
to investigate mechanisms of infertility
and oocyte maturation, as well as for
development and characterisation of
human embryonic stem cell lines.
- Researchers at the Weatherall
Institute of Molecular Medicine,
Oxford, are using Cell-IQ to study multipotent
live cells during differentiation. The
Institute is a world leader in translational
medical research and, in this project,
the Molecular Haematology Unit aims
to understand the signalling pathways
involved in haematopoiesis.
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For more information
visit:
Cell-IQ - system overview |
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For
more information on TAP Biosystems products
and key applications: |
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View the
full range of
key application areas |
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Learn more
about our product range -
the TAP Biosystems Interactive Product Selector |
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Discuss
your requirements with Ian
Ransome, Sales Director |
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