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ambr - system overview
ambr™ mimics the characteristics of classical bioreactors at microscale (10-15ml), by using cost effective, disposable micro-bioreactors, controlled by an automated workstation.
  ambr enables the rapid evaluation of multiple bioreactor cultures at microscale, increasing productivity in cell line development with significant savings on materials and labour.

Central to the system is the new ambr micro bioreactor – specifically designed to mimic the characteristics of a larger scale bioreactor.
  To learn more about the unique ambr micro bioreactor design, and to view key processes from load of media to sampling - take an interactive tour.
  ambr micro bioreactor 'Interactive Tour'

 

Following extensive R&D in collaboration with leading bioprocessing groups, the first automated ambr workstations are now available – offering parallel processing and evaluation of 24 OR 48 bioreactor experiments in an automated bench top system.
 
  • Closed loop control of pH and DO with independent control of O2 and CO2 for each vessel
  • Automated liquid handling for reactor set-up, feeds, base addition and sampling
  • Easy installation into laminar flow hood allowing aseptic operation
  • Optional integrated cell viability analysis
 
  • A better tool for cell line selection and development - closely mimics the conditions of larger scale bioreactors
  • Simplified adoption of Quality by Design (QbD) principles for cell culture development
  • Significant reduction in cost per experiment
  • More experiments with less operator time for set up and clean down
 
  • Cell line selection
  • Cell line stability
  • Media feed strategies
  • Process robustness experimentation in support of ‘quailty by design‘ studies
  • Automation of DOE approaches to process optimisation
  ambr offers an accurate and cost-effective approach to replicating bioreactor conditions, and can be used as a microscale model for a wide range of upstream processes such as cell line selection and process optimisation.
  For more information on ambr:
  Get more detail on the system's key applications:
process development & scale up and cell line selection & development
  Discuss your requirements with Ian Ransome, Sales Director
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